Effect of dietary fat on the lipid and cholesterol level in blood, liver and tissues of rat[s]
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Effect of dietary fat on the lipid and cholesterol level in blood, liver and tissues of rat[s] final technical report, 1971-1974. by R. Pant

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Published by University of Allahabad, Dept. of Biochemistry in Allahabad .
Written in English


  • Blood lipids.,
  • Rats -- Physiology.,
  • Blood cholesterol.,
  • Arteriosclerosis.

Book details:

Edition Notes

ContributionsUniversity of Allahabad. Biochemistry Section.
The Physical Object
Pagination35 l.
Number of Pages35
ID Numbers
Open LibraryOL15399777M

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  Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the world. Hydrogen sulfide (H2S) plays an important role in physiology and pathophysiology of liver. However, whether exogenous H2S could mitigate the hepatic steatosis in mice remains unclear. The aim of this study is to evaluate the effects of H2S on fatty liver. C57BL/6 mice were fed with either a high-fat diet Cited by: Mulberry leaves are the dried leaves of Morus alba L., flavonoids from mulberry leaves (MLF) has showed regulatory effect on abnormal lipid metabolism, but the regulatory mechanism of MLF on cholesterol metabolism is still missing. This study was designed to investigate the effect of MLF and its active metabolite quercetin on regulating cholesterol disorders.   Liver cholesterol levels were doubled in mice on HFD compared with mice fed SC in the sham or 75% SBR groups. Liver free fatty acid levels were also doubled in mice receiving sham surgery compared with those receiving 75% resection. Resection did not affect liver lipid levels regardless of diet type. Download: Download high-res image (KB)Author: Emily J. Onufer, Yong Hyun Han, Rafael S. Czepielewski, Cathleen M. Courtney, Stephanie Sutton, Gwen.   In present study, we expanded lard included diet research to sunflower oil on effects of lipid accumulation in adipose tissue, serum, and liver, mainly focus on different types of oil/fat diet on liver lipids metabolism. Dietary guidelines recommended that the proportion of calories derived from fats should be higher than 20% but lower than 30%.

  Intrahepatocellular lipids. Evidence from human studies suggests that in a high simple carbohydrate diet the liver quickly accumulates fat. Sevastianova et al[] evaluated 16 overweight subjects that in addition to their usual diet ingested kcal/d from simple carbohydrate (candy, pineapple juice, sugar-sweetened soft drinks) for 3 wk, and, thereafter, were placed on a hypocaloric diet . We investigated the dose-dependent effects of dietary ωPUFA supplementation, given as krill oil (KO), on metabolic parameters in high fat diet (HFD)-fed mice and, in parallel, on the levels, in inguinal and epididymal adipose tissue (AT), liver, gastrocnemius muscle, kidneys and heart, of: 1) the endocannabinoids, anandamide and 2. The present study was designed to test the hypothesis that in the liver, excessive fat accumulation impairs cholesterol metabolism mainly by altering the low-density lipoprotein-receptor (LDL-R) pathway. Young male Wistar rats were fed standard (SD), high fat (HFD; 60% kcal) or Western (WD; 40% fat + 35% sucrose (% fructose)) diets for 2 or 6 weeks. Weight gain (~ 40 g) was observed only. cholesterol-7α-hydroxylase (CYP7A1) [8]. Under the state of NAFLD, excessive lipid accumulation leads to steatosis in liver, and causes the up-regulation of SREBP2 and HMGCR, which results in cholesterol over-production [9].Atthesametime,theincrease of cholesterol content in the liver will reduce the conversion rate of bile acid and reduce.

However, an unhealthy diet not only lacks fruits and vegetables, i.e. the primary dietary sources of vitamin C, but also tends to contain high levels of TAG and cholesterol. In fact, blood levels of cholesterol and TAG are apparently affected by the concentration of vitamin C since both the activity of the rate-limiting enzyme, 7α-hydroxylase. The dietary fat source and fat level may alter the effects of dietary Zn depletion on growth rate and lipid metabolism. Bettger et al. [ 4 ] found that dietary substitution of 5% hydrogenated coconut oil for corn oil as a source of essential fatty acids improved the growth of young rats, suggesting an interaction between these nutrients. Apo B is combined with lipid in the liver by the. terrelated effects of dietary cholesterol and fat upon human. blood lipid levels, and tissue fatty acid composi-. The breakdown of fructose in the liver does more than lead to the buildup of fat. It also: elevates triglycerides. increases harmful LDL (so-called bad cholesterol) promotes the buildup of fat around organs (visceral fat) increases blood pressure. makes tissues insulin-resistant, a precursor to diabetes.